2019年 IAAO

国際フォーラム2019(IAAO2019)

Theme:The Front Line of Innovation in Cancer Research and Therapy

Opening Remarks

Osamu Nagayama
(Tokyo Biochemical Research Foundation)

Opening Comment

▶ Combination Therapy with Immuno-Oncology Drugs

Speaker:
Bruce A. Chabner
(Harvard Medical School, USA)
Chair/Moderator:
Yasuo Ikeda
(Waseda University, Japan)

Breakthroughs in Cancer Immunology and Immunotherapy

▶ What’s Next in Cancer Immunotherapy

Speaker:
Antoni Ribas
(University of California, Los Angeles, USA)
Chair/Moderator:
Yusuke Nakamura
(Japanese Foundation for Cancer Research, Japan)

▶ Targeting Regulatory T cells for Tumor Immunity

Speaker:
Shimon Sakaguchi
(Immunology Frontier Research Center, Osaka Univ., Japan)
Chair/Moderator:
Ryuzo Ueda
(Aichi Medical University, Japan)

▶ Enterophages: Newcomers in Immuno-Oncology 2.0

Speaker:
Laurence Zitvogel
(Gustave Roussy, France)
Chair/Moderator:
Noboru Yamamoto
(National Cancer Center Hospital, Japan)

▶ Regeneration of Antigen-Specific Cytotoxic T cells with an iPSC Technology

Speaker:
Shin Kaneko
(Center for iPS Cell Research and Application, Kyoto University, Japan)
Chair/Moderator:
Mitsuaki Yoshida
(Japanese Foundation for Cancer Research, Japan)

Novel Targets for Cancer Drug Development

▶ Predictive Markers for Immunotherapy Including EGFR and ALK Mutants

Speaker:
Bruce E. Johnson
(Dana-Farber Cancer Institute, USA)
Chair/Moderator:
Makoto Ogawa
(Aichi Cancer Center, Japan)

▶ Stromal Fibroblasts Detect Genomic Stress in Cancer Cells and Modulate Therapy Responses

Speaker:
Erik Sahai
(Francis Crick Institute, UK)
Chair/Moderator:
Kohei Miyazono
(The University of Tokyo, Japan)

Cancer Genomics and Precision Oncology

▶ Precision Pediatric Cancer Medicine

Speaker:
Elaine R. Mardis
(Nationwide Children’s Hospital, USA)
Chair/Moderator:
Hiroyuki Mano
(National Cancer Center Research Institute, Japan)

▶ Next-Generation Approaches to Assessing Hereditary Cancer Risk in the Genome Era

Speaker:
James M. Ford
(Stanford University School of Medicine, USA)
Chair/Moderator:
Hiroyuki Aburatani
(The University of Tokyo, Japan)

Translational Research in Precision Oncology

▶ Fostering Precision Medicine in Selected Subpopulations of Patients with CRC

Speaker:
Josep Tabernero
(Vall d’Hebron University Hospital, Spain)
Chair/Moderator:
Tomomitsu Hotta
(National Cancer Center, Japan)

▶ Evolving Paradigms of Precision Medicine in the Clinic

Speaker:
David Hyman
(Memorial Sloan Kettering Cancer Center, USA)
Chair/Moderator:
Hironobu Minami
(Kobe University, Japan)

Targeting Mutant RAS

▶ A Novel Model for Oncogenic Activity of ERK Signal Activation in Human Cancer

Speaker:
Neal Rosen
(Memorial Sloan Kettering Cancer Center, USA)
Chair/Moderator:
Chikashi Ishioka
(Tohoku University, Japan)

▶ Discovery of Direct Inhibitors of the Human Oncogene, KRAS (G12C)

Speaker:
Kevan M. Shokat
(University of California, San Francisco, USA)
Chair/Moderator:
Kiyohiko Hatake
(International University of Health and Welfare, Japan)

▶ Targeting the RAS Pathway with SHP2 Inhibitors

Speaker:
Benjamin G. Neel
(NYU Langone Health, USA)
Chair/Moderator:
Masakazu Toi
(Kyoto University, Japan)

Closing Remarks

Neal Rosen
(Memorial Sloan Kettering Cancer Center, USA)
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