2015年　IAAO

Theme：Forefront of Oncology Care: Discovery, Development and HTA

Opening Remarks

Osamu Nagayama, Chairman Chugai Academy for Advanced Oncology

1. Epigenetics

▶ Epigenetic Therapy – A Means to Prime for Responses to Immune Checkpoint and Other Cancer Therapies?

Speaker: Stephen B. Baylin, MD Johns Hopkins University, USA Chair: Chikashi Ishioka, MD Tohoku University, Japan

▶Targeting Epigenetic Mechanisms in Cancer

Speaker: Scott Armstrong, MD, PhD Memorial Sloan-Kettering Cancer Center, USA Chair: Kiyohiko Hatake, MD, PhD Cancer Institute Hospital, Japan

2. Molecular Targets and Therapy

▶Comprehensive Genomic Profiles of Small Cell Lung Cancer and Other Pulmonary Neuroendocrine Tumors

Speaker: Julie George, PhD University of Cologne, Germany Chair: Hiroyuki Mano, MD, PhD The University of Tokyo, Japan

▶The Evolution of Genotypic Characterization and Targeted Therapy in Lung Cancer

Speaker: Bruce E. Johnson, MD Harvard Medical School, USA Chair: Mitsuaki Yoshida, PhD Japanese Foundation For Cancer Research, Japan

3. Radiation and Thyroid Cancer

▶Radiation and Thyroid Cancer; lessons learned from Hiroshima, Nagasaki and Chernobyl to Fukushima

Speaker: Shunichi Yamashita, MD, PhD Nagasaki University, Japan Chair: James A. Fagin, MD Memorial Sloan-Kettering Cancer Center, USA

▶Molecular Pathogenesis of Radiation-Induced and Sporadic Thyroid Cancers: Implications for Mechanism-Based Therapies

Speaker: James A. Fagin, MD Memorial Sloan-Kettering Cancer Center, USA Chair: Shunichi Yamashita, MD, PhD Nagasaki University, Japan

4. Progress in Breast Cancer Therapy

▶Hormone Resistant Breast Cancer

Speaker: Sarat Chandarlapaty, MD, PhD Memorial Sloan-Kettering Cancer Center, USA Chair: Masakazu Toi, MD, PhD Kyoto University, Japan

▶Translational Approaches to Optimizing Breast Cancer Therapy

Speaker: Leif Ellisen, MD, PhD Harvard Medical School, USA Chair: Yuko Kitagawa, MD, PhD Keio University, Japan

5. “Usefulness” of New Medicines

▶Dealing with the Successes and Failures of Targeted Therapy

Speaker: Bruce A. Chabner, MD Harvard Medical School, USA Chair: Makoto Ogawa, MD Aichi Cancer Center, Japan

▶Health Technology Assessment in Cancer: Driving Efficiency and Efficacy, but at what cost?

Speaker: Patrick Johnston, MD, PhD Queen’s University Belfast, UK Chair: Yasuhiro Fujiwara, MD, PhD National Cancer Center, Japan

6. Tumor Immunotherapy

▶Immunotherapy for Lung Cancer and New Treatment Paradigm

Speaker: Alan B. Sandler, MD Genentech Inc., USA Chair: Nagahiro Saijo, MD, PhD Japanese Society of Medical Oncology, Japan

▶CAR Therapy: The CD19 Paradigm and Beyond

Speaker: Michel Sadelain, MD, PhD Memorial Sloan-Kettering Cancer Center, USA Chair: Ryuzo Ueda, MD, PhD Aichi Medical University, Japan