2016年　IAAO

国際フォーラム2016（IAAO2016）

Theme：Dynamisms in Innovations for Precision Medicine and
Novel Approaches for Cancer Therapy

Opening Remarks

201201 Osamu Nagayama, Chairman
Chugai Academy for Advanced Oncology

1. Epigenetics

▶Personalized Cancer Detection and Monitoring Using Deep
Sequencing of Circulating Tumor DNA

Speaker:
Ash A. Alizadeh, MD, PhD
(Stanford School of Medicine, USA)
Chair:
Kiyohiko Hatake, MD, PhD
(Cancer Institute Hospital, Japan)

▶Multiplex and Whole-Genome Approaches Testing for Germline Cancer Susceptibility Gene Mutations

Speaker:
James M. Ford, MD
(Stanford School of Medicine, USA)
Chair:
Mitsuaki Yoshida, PhD
(Japanese Foundation For Cancer Research, Japan)

▶ Challenges of Comprehensive Genomic Profiling, Immunotherapy and the Liquid Biopsy to Inform Treatment Decisions for Patients with Cancer

Speaker:
Philip J. Stephens, PhD
(Foundation Medicine Inc., USA)
Chair:
Hiroyuki Mano, MD, PhD
(The University of Tokyo, Japan)

2. Cancer Epigenetics

▶The Cancer Epigenome – Scenarios for Designing Therapies

Speaker:
Stephen B. Baylin, MD
(Johns Hopkins University, USA)
Chair:
Chikashi Ishioka, MD
(Tohoku University, Japan)

▶Exploiting the Functions of PARP for Novel Therapeutic Strategies in Cancer

Speaker:
Feyruz V. Rassool, PhD
(University of Maryland School of Medicine, USA)
Chair:
Masakazu Toi, MD, PhD
(Kyoto University, Japan)

3. Advances in Cancer Biology

▶The Molecular Control of Secondary Tumor Formation: EMT, Experimental Tumor Initiation and Metastatic Colonization

Speaker:
Tsukasa Shibue, MD, PhD
(Massachusetts Institute of Technology, USA)
Chair:
Kohei Miyazono, MD, PhD
(The University of Tokyo, Japan)

▶Video Message from Prof. Weinberg

Speaker:
Robert A. Weinberg, PhD
(Whitehead Institute, USA)

▶Organoid Models of Gastrointestinal Cancers

Speaker:
Calvin J. Kuo, MD, PhD
(Stanford School of Medicine, USA)
Chair:
Nagahiro Saijo, MD, PhD
(Japanese Society of Medical Oncology, Japan)

4. Advances in Cancer Therapy

▶New Advances in PDAC Treatment

Speaker:
Manuel Hidalgo, MD, PhD
(Harvard Medical School, USA)
Chair:
Yuko Kitagawa, MD, PhD
Keio University, Japan

▶Inhibiting RAS Tumors

Speaker:
Neal Rosen, MD, PhD
(Memorial Sloan-Kettering Cancer Center, USA)
Chair:
Hitoshi Nakagama, MD, PhD
(National Cancer Center, Japan)

5. Novel Approaches for Cancer Treatment

▶Personalized Cancer Medicine in a Universal Healthcare System

Speaker:
Patrick G. Johnston, MD, PhD
(Queen’s University Belfast, UK)
Chair:
Yasuhiro Fujiwara, MD, PhD
(National Cancer Center, Japan)

▶MicroRNA as Versatile Weapon for Diagnostics and Therapeutics in Oncology

Speaker:
Hitoshi Nakagama, MD, PhD
(National Cancer Center, Japan)
Chair:
Patrick G. Johnston, MD, PhD
(Queen’s University Belfast, UK)

▶Cutting Livers and Genes

Speaker:
Kenneth K. Tanabe, MD
(Harvard Medical School, USA)
Chair:
Ryuzo Ueda, MD, PhD
(Aichi Medical University, Japan)

6. Future Direction of Cancer Research and Therapy

▶The Landscape for Future Progress Against Cancer

Speaker:
Bruce A. Chabner, MD
(Harvard Medical School, USA)
Chair:
Makoto Ogawa, MD
(Aichi Cancer Center, Japan)
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