2017年　IAAO

Theme：Paradigm Shift in Therapeutic Strategies and Novel Treatments for Cancer

Opening Remarks

Osamu Nagayama, Chairman Chugai Academy for Advanced Oncology

1. Innovations in Cancer Research

▶ Lessons Learned from the First Two Decades of Targeted Therapy

Speaker: Bruce A. Chabner (Harvard Medical School, USA) Chair/Moderator: Makoto Ogawa (Aichi Cancer Center, Japan)

2. New Paradigm in Epigenetics

▶ Role of Mutations in Epigenetic Modifiers in Myeloid Malignancies and Therapeutics Response

Speaker: Ross L. Levine (Memorial Sloan Kettering Cancer Center, USA) Chair/Moderator: Chikashi Ishioka (Tohoku University, Japan)

▶ Transcriptional Regulation of Cell Identity and its Misregulation in Cancer

Speaker: Brian J. Abraham (Whitehead Institute, USA) Chair/Moderator: Hiroyuki Mano (The University of Tokyo, Japan)

3. Next Stage in Cancer Immunotherapy

▶ How Melanoma Responds and Resists PD-1 Blockade

Speaker: Antoni Ribas (University of California Los Angeles, USA) Chair/Moderator: Nagahiro Saijo (Japanese Society of Medical Oncology, Japan)

▶ Checkpoint Blockade for Melanoma: What’s New

Speaker: Jedd D. Wolchok (Memorial Sloan Kettering Cancer Center, USA) Chair/Moderator: Hiroyoshi Nishikawa (National Cancer Center, Japan)

▶ Nutrition, Immunity and Cancer

Speaker: Guido Kroemer (Institut National de la Santé et de la Recherche Médicale, France) Chair/Moderator: Ryuzo Ueda (Aichi Medical University, Japan)

4. New Molecular Targeted Drugs

▶ Allele Specific Precision Medicine for ERK-Driven Tumors

Speaker: Neal Rosen (Memorial Sloan Kettering Cancer Center, USA) Chair/Moderator: Mitsuaki Yoshida (Japanese Foundation For Cancer Research, Japan)

▶ Targeting DNA Repair in Cancer Therapy

Speaker: Alan D. D’Andrea (Dana-Farber Cancer Institute, USA) Chair/Moderator: Kohei Miyazono (The University of Tokyo, Japan)

▶ Cyclin D-Dependent Effects of CDK4/6 Inhibitors in Cancer

Speaker: Charles J. Sherr (St. Jude Children’s Research Hospital, USA) Chair/Moderator: Masakazu Toi (Kyoto University, Japan)

5. Cancer Genomics Impacts on Clinical Practice and Economics

▶ Genomic Analysis of Tumors in the Clinic: Promises and Challenges

Speaker: Anthony J. Iafrate (Harvard Medical School, USA) Chair/Moderator: Kiyohiko Hatake (Cancer Institute Hospital, Japan)

▶ The Clinical Outcomes and Costs of Precision Oncology

Speaker: Lincoln D. Nadauld (Intermountain Healthcare, USA) Chair/Moderator: Bruce A. Chabner (Harvard Medical School, USA)

▶ A Nation-Wide Genome Screening Consortium for New Agent Development (SCRUM-Japan)

Speaker: Atsushi Ohtsu (National Cancer Center, Japan) Chair/Moderator: Tomomitsu Hotta (National Cancer Center, Japan)

Closing Remarks

Ryuzo Ueda Aichi Medical University, Japan